Ironwood
Discovering medicines that make a difference for patients, creating value for our fellow shareholders, and empowering our passionate team.
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Employees shape our future

At Ironwood, we’re building a team of talented individuals who embrace the incredibly challenging task of making medicines. All our employees are equity holders, which means we are careful stewards of our resources, and we share the responsibility to build and grow this company.

Our core values

  • Ownership: Drive outstanding long-term value.
  • Collaboration: Achieve more together.
  • Innovation: Make a difference for patients.
  • Excellence: Foster greatness in each other.
  • Humanity: Act with honesty, integrity and respect.
  • Have fun!

About our name

Ironwood has always taken the long view: we hope to grow substantial value and, one step at a time, earn the right to build an enduring pharmaceutical company that helps people lead better lives. So we named ourselves after the ironwood tree, which can live for thousands of years in the harshest desert, creating a shaded microclimate in which life thrives. We also like that the word "ironwood" is both hard and soft. Iron like science, is undeniable and strong. Wood, like artistry and humanity, is flexible, adaptive and versatile. The two words together represent our passion for the art and science of making medicines.

Search Careers

Senior Manager, Research Quality Assurance
Senior Manager, Research Quality AssuranceOverview:We are looking for people to join the Ironwood team who are committed and focused on creating medicines for patients with GI diseases. We have three innovative assets, including our in-market product, LINZESS® (linaclotide) which was discovered in-house and is the branded prescription market leader in its class.Ironwood is more than just a company; you will join a group of people who come together with their unique perspectives and talents to create medicines that can improve the lives of patients. You will join a supportive, collaborative group of people who challenge each other to think differently, and to find creative approaches to helping patients. You will join a welcoming environment where equality, diversity, and inclusion are integral to who we are and the values we hold as a company. You will join a company where not only what you do is important but also how you do it is equally as important. We challenge each other respectfully because everyone’s opinion matters, and we believe that the unique attributes and viewpoints of each team member facilitates the development of innovative ideas that can help us to discover and deliver breakthrough therapies for patients. If you want to help us build the next great pharmaceutical company, please apply!Responsibilities:This position is responsible for performing quality assurance activities to ensure that Ironwood Research Quality Assurance activities support our risk-based approach to managing quality and compliance for Good Clinical Practice (GCP), Good Laboratory Practice (GLP) and Good Pharmacovigilance Practice (GVP).You will be responsible for managing the RQA audit schedule and supporting audits of documents, clinical sites and vendors. This includes managing contracts and oversight for 3rd party auditors, scheduling, preparation, execution, and audit response management.Using quality metrics, you will prepare, analyze and present the output of quality and compliance trends to identify and support process improvements.Support Ironwood’s inspection readiness and regulatory inspectionsParticipate in the development and updates to RQA SOPs, Work Instructions and templatesRepresent RQA in cross-functional settings, including participation on study teams to assist them with managing compliance and quality expectations.Assist RQA Leadership in managing budgets, performance, and timelines.Up to 20% domestic and international travel may be required.Minimum Qualifications:A minimum of a B.S degree or higher in life sciences or allied health.At least eight (8) plus years of experience in pharmaceutical clinical research or development, with a minimum of two (2) years in a Quality Assurance function.Working knowledge of pharmaceutical/biotech GCP regulatory requirements.Strong organizational and interpersonal skills with the ability to build positive relationships with internal and external stakeholders using effective communication, influencing, conflict resolution, critical thinking and problem-solving skills.Ability to work independently and collaboratively to manage challenging objectives and apply quality principles to moderate and complex situations.Preferred qualifications:Experience conducting audits and managing 3rd party auditors is preferred.Relevant GLP or GVP experience is desired.Ironwood is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
Senior Manager, Research Quality Assurance
Senior Manager, Research Quality AssuranceOverview:We are looking for people to join the Ironwood team who are committed and focused on creating medicines for patients with GI diseases. We have three innovative assets, including our in-market product, LINZESS® (linaclotide) which was discovered in-house and is the branded prescription market leader in its class.Ironwood is more than just a company; you will join a group of people who come together with their unique perspectives and talents to create medicines that can improve the lives of patients. You will join a supportive, collaborative group of people who challenge each other to think differently, and to find creative approaches to helping patients. You will join a welcoming environment where equality, diversity, and inclusion are integral to who we are and the values we hold as a company. You will join a company where not only what you do is important but also how you do it is equally as important. We challenge each other respectfully because everyone’s opinion matters, and we believe that the unique attributes and viewpoints of each team member facilitates the development of innovative ideas that can help us to discover and deliver breakthrough therapies for patients. If you want to help us build the next great pharmaceutical company, please apply!Responsibilities:This position is responsible for performing quality assurance activities to ensure that Ironwood Research Quality Assurance activities support our risk-based approach to managing quality and compliance for Good Clinical Practice (GCP), Good Laboratory Practice (GLP) and Good Pharmacovigilance Practice (GVP).You will be responsible for managing the RQA audit schedule and supporting audits of documents, clinical sites and vendors. This includes managing contracts and oversight for 3rd party auditors, scheduling, preparation, execution, and audit response management.Using quality metrics, you will prepare, analyze and present the output of quality and compliance trends to identify and support process improvements.Support Ironwood’s inspection readiness and regulatory inspectionsParticipate in the development and updates to RQA SOPs, Work Instructions and templatesRepresent RQA in cross-functional settings, including participation on study teams to assist them with managing compliance and quality expectations.Assist RQA Leadership in managing budgets, performance, and timelines.Up to 20% domestic and international travel may be required.Minimum Qualifications:A minimum of a B.S degree or higher in life sciences or allied health.At least eight (8) plus years of experience in pharmaceutical clinical research or development, with a minimum of two (2) years in a Quality Assurance function.Working knowledge of pharmaceutical/biotech GCP regulatory requirements.Strong organizational and interpersonal skills with the ability to build positive relationships with internal and external stakeholders using effective communication, influencing, conflict resolution, critical thinking and problem-solving skills.Ability to work independently and collaboratively to manage challenging objectives and apply quality principles to moderate and complex situations.Preferred qualifications:Experience conducting audits and managing 3rd party auditors is preferred.Relevant GLP or GVP experience is desired.Ironwood is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
Associate Director, Pharmaceutical Development & Manufacturing Sciences
Associate Director, Pharmaceutical Development & Manufacturing Sciences (PDMS)Functional Area: CMC Analytical DevelopmentPosition description:The successful candidate will lead the CMC Analytical Development for early and late phase drug product candidates from pre-clinical through technical transfer and commercialization. The Associate Director will be responsible for planning and on time completion of a variety of analytical development and testing activities including management of deliverables and ongoing risk mitigation. The incumbent must possess a strong AD expertise and good technical understanding of the inter-disciplinary nature of drug development demonstrated by previous experience. She/he will collaborate closely with cross-functional internal and primarily external (CDMOs) team members in CMC development, Regulatory, Quality control and assurance, Supply Chain & Manufacturing Operations during all phases of product development, technology transfer, registration, validation and commercial manufacturing. The incumbent will manage CDMOs analytical and stability activities, continuous improvement and life cycle management of testing and characterization methods as well as be responsible for authoring and/or review of IND/NDA submissions. We welcome candidates interested in joining a highly collaborative development team, contributing toward our goal of bringing high quality human medicines to the marketplace. This position will report to Director, PDMS.Responsibilities:Lead analytical development activities across all stages of development for drug substance and drug productManage and oversee analytical development, release, and stability activities at supporting CROs and CMOsDevelop analytical release and stability methods in collaboration with CROs and CMOsReview and approve validation protocols, reports, and associated dataRepresent PDMS as an analytical subject matter expert at technical meetingsDeliver with a high degree of accuracy and clarity, impactful advice and expert opinions on relevant analytical dataSupport CRO/CMO investigations and provide expert guidance and troubleshooting advice when requiredDevelop phase appropriate data supported specifications for raw materials, drug substance, and drug productsOversee analytical methods transfers and validations between CROs and CMOsReview and approve stability protocols, reports, and associated dataAuthor analytical development reports and the analytical section of regulatory submissions (IND, NDA)Author, review, and approve GMP change controls, deviations, and investigations, maintaining a high degree of compliance with regulatory requirementsRepresent the company to partners and suppliers in the area of expertiseRequirements:Ph.D. in Chemistry (or relevant scientific discipline) with 10+ years of relevant experience or a BS/MS in Chemistry with 15+ years of relevant experienceProven experience developing dissolution methods for poorly soluble APIs for extended and delayed-release drug product formulationsA well-grounded foundation in a wide range of other analytical techniques such as NMR, UV, and IR spectroscopy, and physical testing with a strong understanding of the underlying chemistryIn-depth knowledge and working experience applying separation science, including but not limited to reverse and normal phase, ion exchange, and size exclusion chromatographyExcellent data analysis skills and ability to make recommendations that impact the scientific and business goals of the companyGood understanding of ICH, FDA and USP guidelines is essential, including the ability to apply the guidelines in the context of the stage of pharmaceutical developmentStrong oral and written communication skills with experience in writing SOPs, technical reports, and related documents, including regulatory filingsAbility to articulate complex issues and ideas to senior management with clarity to enable understanding and directionAbility to influence cross-functionally to enable improvements and high performance throughout Development and OperationsAbility to work in a fast pace environment, manage priorities, and maintain timelines for multiple activities, both in both a team/matrix environment as well as independentlyExperience supporting pre-formulation and solid-state characterization a plusTravel to manufacturing and analytical testing sites will be required periodicallyIronwood Pharmaceuticals is an equal opportunity employer welcoming diversity in our workforce.
Associate Director, Pharmaceutical Development & Manufacturing Sciences
Associate Director, Pharmaceutical Development & Manufacturing Sciences (PDMS)Functional Area: CMC Analytical DevelopmentPosition description:The successful candidate will lead the CMC Analytical Development for early and late phase drug product candidates from pre-clinical through technical transfer and commercialization. The Associate Director will be responsible for planning and on time completion of a variety of analytical development and testing activities including management of deliverables and ongoing risk mitigation. The incumbent must possess a strong AD expertise and good technical understanding of the inter-disciplinary nature of drug development demonstrated by previous experience. She/he will collaborate closely with cross-functional internal and primarily external (CDMOs) team members in CMC development, Regulatory, Quality control and assurance, Supply Chain & Manufacturing Operations during all phases of product development, technology transfer, registration, validation and commercial manufacturing. The incumbent will manage CDMOs analytical and stability activities, continuous improvement and life cycle management of testing and characterization methods as well as be responsible for authoring and/or review of IND/NDA submissions. We welcome candidates interested in joining a highly collaborative development team, contributing toward our goal of bringing high quality human medicines to the marketplace. This position will report to Director, PDMS.Responsibilities:Lead analytical development activities across all stages of development for drug substance and drug productManage and oversee analytical development, release, and stability activities at supporting CROs and CMOsDevelop analytical release and stability methods in collaboration with CROs and CMOsReview and approve validation protocols, reports, and associated dataRepresent PDMS as an analytical subject matter expert at technical meetingsDeliver with a high degree of accuracy and clarity, impactful advice and expert opinions on relevant analytical dataSupport CRO/CMO investigations and provide expert guidance and troubleshooting advice when requiredDevelop phase appropriate data supported specifications for raw materials, drug substance, and drug productsOversee analytical methods transfers and validations between CROs and CMOsReview and approve stability protocols, reports, and associated dataAuthor analytical development reports and the analytical section of regulatory submissions (IND, NDA)Author, review, and approve GMP change controls, deviations, and investigations, maintaining a high degree of compliance with regulatory requirementsRepresent the company to partners and suppliers in the area of expertiseRequirements:Ph.D. in Chemistry (or relevant scientific discipline) with 10+ years of relevant experience or a BS/MS in Chemistry with 15+ years of relevant experienceProven experience developing dissolution methods for poorly soluble APIs for extended and delayed-release drug product formulationsA well-grounded foundation in a wide range of other analytical techniques such as NMR, UV, and IR spectroscopy, and physical testing with a strong understanding of the underlying chemistryIn-depth knowledge and working experience applying separation science, including but not limited to reverse and normal phase, ion exchange, and size exclusion chromatographyExcellent data analysis skills and ability to make recommendations that impact the scientific and business goals of the companyGood understanding of ICH, FDA and USP guidelines is essential, including the ability to apply the guidelines in the context of the stage of pharmaceutical developmentStrong oral and written communication skills with experience in writing SOPs, technical reports, and related documents, including regulatory filingsAbility to articulate complex issues and ideas to senior management with clarity to enable understanding and directionAbility to influence cross-functionally to enable improvements and high performance throughout Development and OperationsAbility to work in a fast pace environment, manage priorities, and maintain timelines for multiple activities, both in both a team/matrix environment as well as independentlyExperience supporting pre-formulation and solid-state characterization a plusTravel to manufacturing and analytical testing sites will be required periodicallyIronwood Pharmaceuticals is an equal opportunity employer welcoming diversity in our workforce.
Clinical Sales Specialist- Syracuse, NY
Clinical Sales SpecialistWe are looking for people to join the Ironwood team who are committed and focused on creating medicines for patients with GI diseases. We have three innovative assets, including our in-market product, LINZESS® (linaclotide) which was discovered in-house and is the branded prescription market leader in its class.Ironwood is more than just a company; you will join a group of people who come together with their unique perspectives and talents to create medicines that can improve the lives of patients. You will join a supportive, collaborative group of people who challenge each other to think differently, and to find creative approaches to helping patients. You will join a welcoming environment where equality, diversity, and inclusion are integral to who we are and the values we hold as a company. You will join a company where not only what you do is important but also how you do it is equally as important. We challenge each other respectfully because everyone’s opinion matters and we believe that the unique attributes and viewpoints of each team member facilitates the development of innovative ideas that can help us to discover and deliver breakthrough therapies for patients. If you want to help us build the next great pharmaceutical company please apply!Functional area: CommercialPosition Description:Ironwood takes a science advancing “patient first” approach to business activities. When we say we are patient focused, we mean it. To that end, we are currently seeking experienced sales professionals with an outstanding history of sales performance and high integrity. The ideal candidate will have the passion to educate, a desire to establish value-based customer relationships, and an ability to collaborate with our partner(s) in an effort to improve care for patients. This position will call on gastroenterologists and primary care physicians and will report to a Regional Sales Manager.Responsibilities:Develop superior product and disease state knowledge and effectively educate and engage healthcare professionals in dialogue about clinical evidence, approved indications, and product efficacy/safety profiles to support on-label prescribing for appropriate patients.Representative must demonstrate a strong understanding of relevant disease states and possess a solid ability to communicate necessary technical, scientific, and product and disease management information to customers.Ability to effectively engage in product discussions in accordance with Ironwood’s selling approachDrive sales performance in a compliant manner and work to meet or exceed territory sales goals through execution of regional and national marketing strategiesRegularly use a variety of analytical tools to understand and evaluate the business in order to best determine how to accomplish sales objectives.Work collaboratively with Ironwood personnel and co-promote to achieve common objectives through coordinated selling efforts.Provide timely and competent administrative management of work hours, sales call data, customer objectives, communication responses, synchronization, sample management, and travel, meal and other expense reporting.Key account management: Total office callUnderstands that at Ironwood, compliance is an expectation for which we are all held accountable and this philosophy extends to our sales efforts. We seek sales professionals who understand that we operate in a heavily regulated industry, that as an Ironwood employee we are all owners of the company, and that to protect the company that we own we will only sell our products in a manner that complies with all applicable laws, rules and regulations.Ironwood’s Clinical Sales Specialist (CSS) competency model has been crafted in partnership with commercial leadership, the sales team, and those in the field. Taken as a whole, this competency model is designed to enable our CSSs to win the right way in the market and make a positive impact for customers and patients. Clinical Sales Specialist (CSS) CompetenciesLeads, plans and operates as an ownerUnderstands the business, takes responsibility, and is held accountable for ethical, compliant selling, decision-making, business planning, and implementation which impacts both short- and long-term outcomes.Maximizes results through collaborationHas the mindset that collaboration is critical to Ironwood’s success. Actions and behaviors enable one’s team and partners to win. Teams up with others inside and outside of Ironwood to improve personal, team and organizational performance.Impacts outcomes through trusted customer relationshipsHelps improve patient care by understanding customer needs and building trusted long-term relationships.Influences customer behavior through the Ironwood buying processInfluences customer behaviors by compliantly engaging with our HCPs to help them clearly understand how our products can improve care with the appropriate patients.Personal leadership and accountabilityDemonstrates drive and passion to continuously improve - learns from setbacks, takes on personal development opportunities and accountability and looks for ways to improve.Basic Qualifications:Bachelor’s degree Associate CSS: Minimum of 1 year of pharmaceutical sales experience CSS: Minimum of 4 years of pharmaceutical sales experience Senior CSS: Minimum of 10 years of pharmaceutical sales experience Possess a current and valid driver’s license at all times Able to operate a motor vehicleTravel over a broad geography Preferred Qualifications:Exceptional communication skills (oral and written); ability to articulate and implement tactical product and territory strategies.Specialty sales preferredAbility to prioritize tasks, problem solve and work with co-promote partner(s) to make strategic business decisions.Strong computer skills (Word, Excel and PowerPoint).Strong analytical skills Demonstrated leadership ability
Clinical Sales Specialist- Syracuse, NY
Clinical Sales SpecialistWe are looking for people to join the Ironwood team who are committed and focused on creating medicines for patients with GI diseases. We have three innovative assets, including our in-market product, LINZESS® (linaclotide) which was discovered in-house and is the branded prescription market leader in its class.Ironwood is more than just a company; you will join a group of people who come together with their unique perspectives and talents to create medicines that can improve the lives of patients. You will join a supportive, collaborative group of people who challenge each other to think differently, and to find creative approaches to helping patients. You will join a welcoming environment where equality, diversity, and inclusion are integral to who we are and the values we hold as a company. You will join a company where not only what you do is important but also how you do it is equally as important. We challenge each other respectfully because everyone’s opinion matters and we believe that the unique attributes and viewpoints of each team member facilitates the development of innovative ideas that can help us to discover and deliver breakthrough therapies for patients. If you want to help us build the next great pharmaceutical company please apply!Functional area: CommercialPosition Description:Ironwood takes a science advancing “patient first” approach to business activities. When we say we are patient focused, we mean it. To that end, we are currently seeking experienced sales professionals with an outstanding history of sales performance and high integrity. The ideal candidate will have the passion to educate, a desire to establish value-based customer relationships, and an ability to collaborate with our partner(s) in an effort to improve care for patients. This position will call on gastroenterologists and primary care physicians and will report to a Regional Sales Manager.Responsibilities:Develop superior product and disease state knowledge and effectively educate and engage healthcare professionals in dialogue about clinical evidence, approved indications, and product efficacy/safety profiles to support on-label prescribing for appropriate patients.Representative must demonstrate a strong understanding of relevant disease states and possess a solid ability to communicate necessary technical, scientific, and product and disease management information to customers.Ability to effectively engage in product discussions in accordance with Ironwood’s selling approachDrive sales performance in a compliant manner and work to meet or exceed territory sales goals through execution of regional and national marketing strategiesRegularly use a variety of analytical tools to understand and evaluate the business in order to best determine how to accomplish sales objectives.Work collaboratively with Ironwood personnel and co-promote to achieve common objectives through coordinated selling efforts.Provide timely and competent administrative management of work hours, sales call data, customer objectives, communication responses, synchronization, sample management, and travel, meal and other expense reporting.Key account management: Total office callUnderstands that at Ironwood, compliance is an expectation for which we are all held accountable and this philosophy extends to our sales efforts. We seek sales professionals who understand that we operate in a heavily regulated industry, that as an Ironwood employee we are all owners of the company, and that to protect the company that we own we will only sell our products in a manner that complies with all applicable laws, rules and regulations.Ironwood’s Clinical Sales Specialist (CSS) competency model has been crafted in partnership with commercial leadership, the sales team, and those in the field. Taken as a whole, this competency model is designed to enable our CSSs to win the right way in the market and make a positive impact for customers and patients. Clinical Sales Specialist (CSS) CompetenciesLeads, plans and operates as an ownerUnderstands the business, takes responsibility, and is held accountable for ethical, compliant selling, decision-making, business planning, and implementation which impacts both short- and long-term outcomes.Maximizes results through collaborationHas the mindset that collaboration is critical to Ironwood’s success. Actions and behaviors enable one’s team and partners to win. Teams up with others inside and outside of Ironwood to improve personal, team and organizational performance.Impacts outcomes through trusted customer relationshipsHelps improve patient care by understanding customer needs and building trusted long-term relationships.Influences customer behavior through the Ironwood buying processInfluences customer behaviors by compliantly engaging with our HCPs to help them clearly understand how our products can improve care with the appropriate patients.Personal leadership and accountabilityDemonstrates drive and passion to continuously improve - learns from setbacks, takes on personal development opportunities and accountability and looks for ways to improve.Basic Qualifications:Bachelor’s degree Associate CSS: Minimum of 1 year of pharmaceutical sales experience CSS: Minimum of 4 years of pharmaceutical sales experience Senior CSS: Minimum of 10 years of pharmaceutical sales experience Possess a current and valid driver’s license at all times Able to operate a motor vehicleTravel over a broad geography Preferred Qualifications:Exceptional communication skills (oral and written); ability to articulate and implement tactical product and territory strategies.Specialty sales preferredAbility to prioritize tasks, problem solve and work with co-promote partner(s) to make strategic business decisions.Strong computer skills (Word, Excel and PowerPoint).Strong analytical skills Demonstrated leadership ability
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